The Gates Foundation and OpenAI have announced a $50 million pilot program aimed at advancing AI capabilities for healthcare in Africa. Named Horizon 1000, the initiative will provide funding, technology, and technical support to implement AI solutions in 1,000 primary healthcare clinics across the continent by 2028. OpenAI CEO Sam Altman emphasized that while AI is a scientific marvel, its true potential lies in improving people’s lives. Bill Gates highlighted the program’s goal of enhancing the quality and efficiency of healthcare, reducing paperwork, and better organizing resources for patients.
The pilot program will initially begin in Rwanda before expanding to Kenya, South Africa, and Nigeria. Rwanda has already been exploring AI to support healthcare workers in disease diagnosis, administrative tasks, and disease trajectory modeling. Rwanda’s Minister of Information, Communication, and Technology and Innovation, Paula Ingabire, noted that the country has invested in technological solutions for over two decades, including providing internet access to around 97% of its population and building foundational digital infrastructure to support AI advancements.
Rwanda aims to develop AI-driven decision-support tools for its more than 60,000 community health workers, particularly to improve malaria diagnosis and predict outbreaks. The country has previously combined drones and AI to address malaria, using drones to locate mosquito breeding sites and AI for disease modeling. Expanding its health workforce has been a priority, and AI tools are expected to support better care delivery and improve administrative efficiency. Additionally, AI will help Rwanda forecast health commodity demand to prevent medicine shortages and optimize resource allocation.
Discussions are also underway with AI companies like Anthropic to create instant health intelligence platforms integrated into national health planning systems. The Global Fund to Fight AIDS, Tuberculosis and Malaria has already invested $170 million in AI-based TB screening over the past four years, with significant impact in settings such as refugee camps where human radiologists are unavailable.
Despite the promise, challenges remain, including limited internet connectivity and power in many African primary healthcare facilities. Experts stress that AI deployment should be problem-driven rather than technology-driven, ensuring tools are practical and usable. Gates and other leaders believe AI adoption may progress faster in low- and middle-income countries, where the need is urgent and resistance to job displacement is lower. The $50 million commitment is seen as a first step toward making AI healthcare support widely accessible to African populations without cost, streamlining processes, and enabling better patient care.





